Hepatitis B is a viral infection of the liver and approximately 1/3 of a billion people world wide have a chronic infection. Chronic Hepatitis B infections can lead to liver cirrhosis, cancer and death. Hepatitis B infections are more common in certain parts of the world with up to 10% of people in SE Asia being affected. Hepatitis B viral disease is incurable and can lead to acute infection and death or liver cirrhosis, liver cancer and death over time. Other symptoms include jaundice ( yellow eyes), weight loss, loss of appetite, tiredness, fever, dark urine and light coloured stools. The best way to reduce the risk of infection is by being vaccinated as it is not always possible to prevent accidents abroad and accident rates are higher abroad and with adventure pursuits. Hepatitis B infection is spread to humans by mixing bodily fluids or blood by accidents, blood transfusions, sexual intercourse, tattooing, acupuncture and reusing needles or medical equipment.